Open Diagnostic Reader (ODR): An affordable, modular 3D-printed platform for standardized imaging and quantitative analysis of rapid diagnostic tests.

Subjective interpretation of control and test line(s) presence and increasingly complex multiplex RDTs with many result combinations highlight the need for interpretation aides. Proprietary hardware is often expensive, fixed to specific tests, and unsuitable in decentralised testing locations.

We present the Open Diagnostic Reader (ODR), a cost-effective (15 – 45 GBP), modular, easy-to-use open-source diagnostic imaging platform. The platform supports multiple lighting modalities (internal, external or no light source); multiple RDTs and disease targets (cholera and Hepatitis E); and multiple diagnostic test use cases (RDTs and agar plates for antimicrobial resistance testing). Designs can be quickly printed (19 – 25 hours) using desktop 3D printers and require only simple or no assembly.