Dataset for "Lipid metabolism links nutrient-exercise timing to insulin sensitivity in overweight men"

This project comprised two experiments. We first assessed the acute metabolic and mRNA responses to manipulating nutrient-exercise timing (Acute Study), followed by a 6-week randomized controlled trial to assess the longer-term adaptations in response to nutrient-exercise timing (Training Study).

We showed that in overweight/obese, but otherwise healthy men (mean±SD for age: 30 ± 10 years for acute study, 35 ± 9 years for training study and BMI: 30.2±3.5 kg/m-2 for acute study, 30.9±4.5 kg/m-2 for training study) a single exercise bout before versus after nutrient provision increased lipid utilization at the whole-body level, but also in both type I (p<0.01) and type II muscle fibers (p=0.02). We then used a 6-week intervention to show sustained, 2-fold increases in lipid utilization with exercise training before versus after nutrient provision (p<0.01).