Replication Data for: B.M. Crosland, M.R. Johnson, and E.A. Matida (2009) Characterization of the Spray Velocities from a Pressurized Metered-Dose Inhaler, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 22(2):85-97 (doi: 10.1089/jamp.2008.0687).

Instantaneous planar velocity measurements were taken and ensemble-averaged at various times during the spray event. The mean spray velocities were shown to be bimodal in time with two velocity peaks.

Planar velocity data were analyzed to produce prescriptive velocity profiles suitable for use in numerical simulations. Statistical comparisons from several thousand spray events indicate that there is no significant difference in measured velocity between i) two brands of pMDI canisters, ii) two similar pMDIs from different lots, and iii) a full pMDI versus an almost-empty pMDI. Further experiments with a secondary air flow of 30 SLPM with and without an added cylindrical spacer deflected the spray downward, but had little effect on the velocity magnitude.