Evodia-rutaecarpa-alkaloids Compounds Database (ECD)

It is reported that this biologically active alkaloid has a wide range of biological activities, including anti-injury, anti obesity, vasodilation, and anti-inflammatory effects. In recent years, it has been found that evodia rutaecarpa alkaloids have antitumor effects on a variety of tumors.

There is increasing evidence that evodia rutaecarpa alkaloids can inhibit the rapid proliferation of tumor cells, induce cell cycle arrest at a certain stage, increase the incidence of apoptosis, promote autophagy, inhibit angiogenesis and migration, and regulate immunotherapy. In order to facilitate the query of the inhibitory effect and mechanism of evodia rutaecarpa alkaloids on common tumor cell lines, and facilitate the subsequent structural modification, with a view to finding evodia rutaecarpa alkaloids with significant tumor inhibitory effects, an anti-tumor database based on a large number of literature reviews was constructed.