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Data · dataset · 2026

Identification and activity assessment of a bioactive peptide QUB-2589 from the skin secretion of Agalychnis annae

Listed in ZivaHub and Deakin Research Online and DMU Figshare — shown once because both records carry DOI 10.17034/32638755.v1

With the global rise of antibiotic resistance posing a significant challenge to the world, the exploration of alternative strategies to combat bacterial infections has become imperative.

Description

Antimicrobial peptides (AMPs) have emerged as promising candidates due to their unique mechanisms of action and potential efficacy. This study was carried out under this field with the aim of discovering a novel antimicrobial peptide.

In this case, a novel peptide called QUB-2589 was identified from the skin secretions of Agalychnis annae using molecular cloning techniques. Following that, the polypeptide was synthesised through solid-phase peptide synthesis (SPPS) and purified via reverse phase high-performance liquid chromatography (HPLC). The molecular mass was confirmed using matrix-assisted laser desorption/ionization time of fight mass spectrometry (MALDI-TOF).

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QUB-2589 underwent a series of bioactivity tests.<br><br><i>Thesis is embargoed until 31 December 2028</i>.

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Mass spectrometry 75%
Provenance · 3 source records, 9 field assertions
SourceKeyLast seenRaw
ZivaHuboai:figshare.com:article/3263875512 d agoJSON v1
Deakin Research Onlineoai:figshare.com:article/3263875512 d agoJSON v1
DMU Figshareoai:figshare.com:article/3263875512 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
concepts[field].local:field:earth-environmentalmapping · figshare dmu ac ukconnector:figshare_dmu_ac_uk@1.0.0
concepts[field].local:field:earth-environmentalmapping · dro deakin edu auconnector:dro_deakin_edu_au@1.0.0
concepts[field].local:field:earth-environmentalmapping · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
concepts[modality].local:modality:mass-spectrometryenrichment · zivahub uct ac zakeyword-concept-rules@1.0.0title+description (75%)
descriptionsource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0/metadata/dc/description
license_textsource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
publication_datesource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
titlesource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0/metadata/dc/title