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Data · dataset · 2026

Scoparone ameliorates metabolic dysfunction-associated fatty liver disease in mice by inhibiting ferroptosis through activation of the Nrf2/GPX4 pathway

Listed in ScienceDB

This dataset is derived from animal and cell experiments on the improvement of metabolic dysfunction-associated fatty liver disease in mice via the inhibition of ferroptosis through the activation of the Nrf2/GPX4 pathway by scoparone.

Description

It systematically records the raw data and processed results of the entire experimental process, providing data support for the conclusions of this study.The dataset contains a total of 10 files, which correspond to the graphical data of 10 figures in the paper as follows: Fig. 1: Liver photographs, HE staining and Oil Red O staining images of hepatic tissues; Fig. 2: Dynamic changes in body weight and food intake of mice; Fig. 3: Serum and hepatic related parameters of mice; Fig. 4: Mitochondrial function parameters of mouse liver; Fig. 5: PCR and Western blot (WB) analysis results of mouse liver-related indicators; Fig. 6: Concentration screening results of SCO and NaOA in cell experiments; Fig. 7: Oil Red O staining images of cells; Fig. 8: Cell-related functional parameters; Fig. 9: ROS staining images, JC-1 staining images and their corresponding fluorescence quantification results of cells; Fig. 10: PCR and Western blot (WB) analysis results of cell-related indicators.

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Disease 75% · Image 65% · Medical biochemistry and metabolomics 68%
Provenance · 1 source records, 14 field assertions
SourceKeyLast seenRaw
ScienceDB10.57760/sciencedb.3625311 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · scidb cnconnector:scidb_cn@1.0.0
concepts[disease].local:disease:diseaseenrichment · scidb cnkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].anzsrc:group:3205enrichment · scidb cntaxonomy-embedding@1.0.0title+keywords+description (68%)
concepts[field].local:field:earth-environmentalmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:engineeringmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:humanitiesmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:life-sciencesmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:medicine-healthmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:social-sciencemapping · scidb cnconnector:scidb_cn@1.0.0
concepts[modality].local:modality:imageenrichment · scidb cnkeyword-concept-rules@1.0.0title+description (65%)
descriptionsource · scidb cnconnector:scidb_cn@1.0.0/metadata/dc/description
license_textsource · scidb cnconnector:scidb_cn@1.0.0
publication_datesource · scidb cnconnector:scidb_cn@1.0.0
titlesource · scidb cnconnector:scidb_cn@1.0.0/metadata/dc/title