Biomimetic Models of the Active Site of the Metalloenzyme Nitrile Hydratase

To illustrate the evolution of knowledge, the author's Precandidacy (1998) and General Exam (1999) papers and a poster (2000) are included. All of the experimental results contained within this PhD thesis have by now been reported in journal articles.

However, this thesis provided room for a much more detailed presentation of the experimental results and their discussion and analysis. {FeNO}6 model compound [chapter 2]: Journal of the American Chemical Society 1998 , 120 , 10996-10997 pubs.acs.org/doi/abs/10.1021/ja981117e Oxygenated Co(III)-thiolate complexes [pages 16-17 & 113-116]: Journal of the American Chemical Society 2000 , 122 , 8299-8300 pubs.acs.org/doi/abs/10.1021/ja0017561 Improved synthesis of tetramethylammonium azide: Croatica Chemica Acta 2001 , 74 , 415-418 public.carnet.hr/ccacaa/CCA-PDF/cca2001/v74-n2/cca_74_2001_415-418_Schweitzer.pdf Reactivity as a function of an Et,Pr or Pr,Pr ligand backbone to model the entatic state of an enzymatic active site [chapter 3]: Inorganic Chemistry 2002 , 41 , 3128-3136 pubs.acs.org/doi/abs/10.1021/ic0109187 Fe(III) complexes of an (Namide)2(Sthiolate)2 ligand [chapter 4]: Inorganic Chemistry 2008 , 47 , 11228-11236 pubs.acs.org/doi/abs/10.1021/ic801704n