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Data · dataset · 2026

<p>Effect of stimulation pattern on SCN phase shift and <i>Per2</i> induction.</p>

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<p><b>A</b>: Phase response curves of the combined signal in the reduced Poincaré model for ventral-only stimulation (green) and simultaneous stimulation of both oscillators (yellow).

Description

Gray shading indicates phases where simultaneous stimulation produces a smaller phase shift than ventral-only stimulation. <b>B</b>: Representative phase-shift decompositions are shown under four conditions, corresponding from left to right to Poincaré CT9, Poincaré CT21, molecular CT18, and molecular CT4.

Within each condition, solid bars represent dual stimulation and hatched bars represent ventral-only stimulation. Yellow, blue, and red bars indicate the phase shifts of the global SCN signal, dorsal, and ventral components, respectively. <b>C</b>: Net <i>Per2</i> phase shift after a 2-hour temperature pulse at CT4, as a function of pulse temperature, for three conditions: dual SCN stimulation (yellow), ventral-only stimulation (green), and homogeneous model (blue). <b>D</b>: Fold increase in <i>Per2</i> expression after stimulation under the same conditions.

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Fold increase was calculated as the ratio of the maximum <i>Per2</i> level after stimulation to the level immediately before stimulation.</p>

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ZivaHuboai:figshare.com:article/3402700512 d agoJSON v1
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