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Structure · dataset · 2026

Antimicrobial polymer coatings to combat infection of medical devices

Listed in ZivaHub and Deakin Research Online and DMU Figshare — shown once because both records carry DOI 10.17034/32639541.v1

Medical devices are vital in modern medicine, but device-associated infections pose significant challenges.

Description

Bacterial adhesion and biofilm formation on device surfaces lead to infections with serious consequences. This thesis focuses on combating prosthetic joint infections (PJIs) and catheter-associated urinary tract infections (CAUTIs).

Releasing-type antibacterial coatings were developed for medical devices to combat microorganisms causing infections. Antibiotic-loaded poly (lactic-co-glycolic acid) (PLGA) polymer films were prepared via airbrushing onto orthopedic implants to address PJIs. PLGA coatings showed controlled antibiotic release, inhibiting bacterial growth for up to a month.

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Weak organic acid (WOA)-loaded poly (lactic acid) (PLA) coatings were developed for indwelling urinary catheters to tackle CAUTIs. WOA-loaded PLA coatings demonstrated antibacterial and antiencrustation effects, inhibiting bacterial adhesion and biofilm formation. The feasibility of forming antimicrobial polymer coatings via airbrush spray coating and dip coating methods was validated, offering potential in reducing device-associated infections in clinical settings.<br><br><i>Thesis is embargoed until 31 July 2029.</i>

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Materials engineering 69%
Provenance · 3 source records, 12 field assertions
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ZivaHuboai:figshare.com:article/326395415 d agoJSON v1
Deakin Research Onlineoai:figshare.com:article/326395415 d agoJSON v1
DMU Figshareoai:figshare.com:article/326395415 d agoJSON v1
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