Omics · dataset · 2025
RNA sequencing of parental lung cancer cells with USP18 treatment
Listed in Teesside University Research Data Repository
RNA-seq data from Liu et al., 2025.
Description
A549 lung cancer cells stably expressing USP18 or empty vector treated with vehicle as a control or β-Lapachonefor 48 hours were harvested to extract total RNA for sequencing. RNA sequencing libraries were prepared using the TruSeq Stranded mRNA ligation protocol and sequenced on an Illumina NextSeq 2000 platform.
Gene expression profiling from the RNA-seq data revealed differentially expressed genes and pathways following β-lapachone treatment in parental lung cancer cells, with or without gain of USP18 expression.
Links
Where it is published
- DOI doi.org/10.17632/7wrrbyzh8p.1 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Earth & Environmental Science · RNA sequencing
- Inferred from text
- Cancer 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/7wrrbyzh8p.1 | 16 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[modality].local:modality:rna-seq | mapping · researchdata tees ac uk | vocabulary-mapper@1.0.0 | keywords['RNA Sequencing'] |
| concepts[modality].local:modality:sequencing | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |