Table · dataset · 2026

<p>Description of the tolerance-based bins, genes, variants, and prior probabilities. The tolerance-based bins used for the DVD and resulting prior probabilities of pathogenicity and benignity as described in the text. o/e is the range of tolerance scores for each bin. Gene and variants are the number of genes and total variants that fall in each bin. L/B and L/P are the number of labeled variants in each bin. P (v is pathogenic) and P (v is benign) are the prior probabilities that a variant is pathogenic or benign in each bin. The X-linked/MT bin is all genes without an o/e score, which is assigned the overall DVD prior.</p>

Listed in ZivaHub and Deakin Research Online and DMU Figshare and HKU DataHub and Swinburne Figshare and DaYta Ya Rona and SUNScholarData and figshare and Loughborough Research Repository and GRANTS Data and UP Research Data Repository — shown once because both records carry DOI 10.1371/journal.pgen.1012085.t001

<p>Description of the tolerance-based bins, genes, variants, and prior probabilities.