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Table · dataset · 2026

Home-based exercise interventions incorporating cardiac rehabilitation principles for people with cancer: a systematic review and meta-analysis

Listed in ZivaHub and Deakin Research Online and HKU DataHub and DaYta Ya Rona and figshare and Loughborough Research Repository and UP Research Data Repository — shown once because both records carry DOI 10.6084/m9.figshare.34030408.v1

<p>People with cancer are at increased cardiovascular risk due to treatment-related cardiotoxicity and shared risk factors.

Description

Exercise-based cardiac rehabilitation (exCR) may mitigate these risks, but access to center-based programs is limited. This systematic review and meta-analysis evaluated the effectiveness, safety, and adherence of home-based exCR in oncology populations.</p> <p>Six databases were searched in January 2025 for randomized controlled trials (RCTs) of home-based exCR in adults with cancer.

Eligible interventions included structured aerobic and/or resistance exercise consistent with established CR guidelines. Primary outcomes were cardiorespiratory fitness (CRF), health-related quality of life (HRQoL), adherence, and safety. Random-effects meta-analyses used standardized mean differences (SMDs).</p> <p> Nine RCTs (632 participants) were included.

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Home-based exCR improved CRF (SMD 0.42; 95% CI 0.09–0.75; <i>I</i>²=62%) and HRQoL (SMD 0.63; 95% CI 0.05–1.22; <i>I</i>²=84%). TESTEX scores indicated generally good methodological and reporting quality (mean 10/15; range 7–13). Adherence exceeded 75% in most studies reporting this outcome, and dropout was 15.2%.

Adverse-event reporting was inconsistent; no clear safety signal emerged, but evidence was insufficient for firm conclusions. Strength and fatigue findings were inconsistent.</p> <p>Home-based exCR appears feasible and may improve CRF and HRQoL in people with cancer, offering an accessible alternative or complement to center-based rehabilitation. Incomplete adverse-event reporting limits safety conclusions.

Future studies should evaluate full, multi-component CR models in oncology.</p>

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Inferred from text
Heart 65%
Provenance · 7 source records, 72 field assertions
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ZivaHuboai:figshare.com:article/3403040812 d agoJSON v1
Deakin Research Onlineoai:figshare.com:article/3403040812 d agoJSON v1
HKU DataHuboai:figshare.com:article/3403040812 d agoJSON v1
DaYta Ya Ronaoai:figshare.com:article/3403040812 d agoJSON v1
figshareoai:figshare.com:article/3403040811 d agoJSON v1
Loughborough Research Repositoryoai:figshare.com:article/3403040811 d agoJSON v1
UP Research Data Repositoryoai:figshare.com:article/3403040811 d agoJSON v1
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