Data · dataset · 2026
Supplementary Figures S1-S17 from LPL-Positive Endothelial Cells Control T-cell Homing in Liver Metastasis
Listed in ZivaHub and Deakin Research Online and DMU Figshare — shown once because both records carry DOI 10.1158/2159-8290.34040886
<p>Supplementary figures S1-S17 and their figure legends.
Description
Figure S1. Endothelial cells regulate effector T cell homing in OVA-B16F10 liver metastases.
Figure S2. Quality control of scRNAseq data of all analyzed ECs. Figure S3.
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Changes in the cluster composition of analyzed ECs following ACT. Figure S4. Annotation of different tumor EC subsets.
Figure S5. scRNAseq-guided molecular characterization of TECs. Figure S6. Genetic deletion of Lpl in ECs and its influence on intratumoral vessels.
Figure S7. Genetic overexpression of Lpl in ECs and its influence on intratumoral vessels. Figure S8.
Effect of endothelial LPL on OT-I T cell infiltration in the OVA-LLC liver metastatic model. Figure S9. Single-cell characterization of the immune landscape of liver metastatic tumors with endothelial LPL intervention.
Figure S10. Characterization of tumor-associated monocytes/macrophages with EC-LPL intervention. Figure S11.
Characterization of intratumoral CD8+ T cells with EC-LPL intervention. Figure S12. Endothelial LPL upregulation results in the activation of molecules related to MHC-I-mediated antigen presentation.
Figure S13. In vivo MHC-I blocking experiment. Figure S14.
Endothelial antigen presentation facilitates T cell infiltration into liver metastatic tumors. Figure S15. Analysis of EC death after ACT of activated OT-I T cells.
Figure S16. Assessment of LPL+ TECs in clinically relevant intervention models. Figure S17.
Staining of LPL on human CRC-derived liver metastatic tumor tissue.</p>
Links
Where it is published
- DOI doi.org/10.1158/2159-8290.34040886 ↗
DOI / persistent id · from zivahub uct ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from zivahub uct ac za
Topics
Provenance · 3 source records, 19 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ZivaHub | oai:figshare.com:article/34040886 | 13 d ago | JSON v1 |
| Deakin Research Online | oai:figshare.com:article/34040886 | 13 d ago | JSON v1 |
| DMU Figshare | oai:figshare.com:article/34040886 | 13 d ago | JSON v1 |
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| concepts[disease].local:disease:cancer | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['Cancer'] |
| concepts[disease].local:disease:cancer | mapping · dro deakin edu au | vocabulary-mapper@1.0.0 | keywords['Cancer'] |
| concepts[field].anzsrc:group:3204 | mapping · zivahub uct ac za | vocabulary-mapper@1.0.0 | keywords['Immunology'] |
| concepts[field].anzsrc:group:3204 | mapping · dro deakin edu au | vocabulary-mapper@1.0.0 | keywords['Immunology'] |
| concepts[field].anzsrc:group:3204 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['Immunology'] |
| concepts[field].local:field:earth-environmental | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| description | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/description |
| license_text | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| publication_date | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| title | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/title |