Data · dataset · 2024
Relationship between intraoperative drop in pulse pressure and minimum mean arterial pressure with postoperative length of stay according to main patients’ characteristics: A retrospective monocentric study
Listed in DataCite
Intraoperative hypotension (IOH) is associated with organ failure.
Description
There is no consensus on the IOH definition, but the recommendations agree on a threshold of mean arterial pressure (MAP) between 60-70 mmHg. Prolonged postoperative length of stay (pLOS) is a surrogate for organ injuries.
Our study focuses on the relationship between IOH and pLOS risk considering the main patient characteristics (sex and age) using a retrospective single-centre cohort study of adult patients having received general anesthesia for a scheduled non-cardiac surgical procedure. pLOS was defined as a LOS higher than the median value (main outcome). Relationships between the IOH variables selected from a previous study (difference between the larger and smaller pulse pressure values (DropPP), minimal MAP (MinMAP), and cumulative time pulse pressure spent above 61mmHg (CumTimePP>61mmHg) and the risk of pLOS are represented by knotted linear splines.
Read the rest (3 more)
Our study examined 9,516 patients. The relationship between DropPP and pLOS risk was pseudolinear with no activation threshold (slope 0.29-0.52%/mmHg). For MinMAP, this relationship describes an activation threshold at 73 mmHg below which the association is linear (slope -0.64%/mmHg).
For CumTimePP>61, the risk of pLOS rapidly rises (initial slope 8.39%/min) up to a saturation threshold at two minutes. Women had a lower pLOS risk and IOH threshold. Older patients had a higher pLOS risk and did not exhibit an IOH threshold.
The IOH threshold (MAP<73 mmHg) is consistent with the existing literature. The variability of PP as well as age and sex are key parameters in pLOS risk.
Links
Where it is published
- Repository landing page datadryad.org/dataset/doi:10.5061/dryad.9zw3r22qj ↗
landing page · from DataCite
- DOI doi.org/10.5061/dryad.9zw3r22qj ↗
DOI / persistent id · from DataCite
Documentation and papers
- Creative Commons Zero v1.0 Universal creativecommons.org/publicdomain/zero/1.0/legalcode ↗
license · from DataCite
Catalogue records · 2
- DataCite API api.datacite.org/dois/10.5061/dryad.9zw3r22qj ↗
metadata API · from DataCite
- DataCite Commons commons.datacite.org/doi.org/10.5061/dryad.9zw3r22qj ↗
catalogue entry · from DataCite
Topics
- Stated by source
- Basic medicine
- Inferred from text
- Longitudinal study 65%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| DataCite | 10.5061/dryad.9zw3r22qj | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| byte_size | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:basic-medicine | source · DataCite | connector:datacite@1.0.0 | |
| concepts[method].local:method:longitudinal-study | enrichment · DataCite | keyword-concept-rules@1.0.0 | title+description (65%) |
| created_date | source · DataCite | connector:datacite@1.0.0 | |
| description | source · DataCite | connector:datacite@1.0.0 | /data/attributes/descriptions |
| license | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| publication_date | source · DataCite | connector:datacite@1.0.0 | /data/attributes/dates |
| title | source · DataCite | connector:datacite@1.0.0 | /data/attributes/titles/0/title |
| version_label | source · DataCite | connector:datacite@1.0.0 |