Replication Data for: Taurine efflux counters the hydrodynamic impact of anaerobic metabolism to protect cardiorespiratory function under acute thermal stress in brook char (Salvelinus fontinalis)

The thermal sensitivity of aerobic metabolism did not differ, and lactate accumulated to a similar degree in both diet treatment groups, indicating that taurine deficiency does not impact energy metabolism. Heart taurine efflux was absent and ventricular muscle osmolality was 40 mOsmol kg-1 22 higher in TD brook char following thermal stress. Swelling and decreased ventricular compliance likely impair diastolic filling to constrain stroke volume in TD fish.

The adrenaline sensitivity of cardiac contractility and the regulation of intracellular pH in brain and liver were also impacted in TD brook char. Taurine efflux appears necessary to counteract the hydrodynamic impact of activating anaerobic metabolism and this process may limit heart function under acute thermal stress.