Table 1_Development of a multidimensional disease burden assessment system for childhood neuroblastoma based on the social determinants of health theory.xlsx

Objective<p>To construct a multidimensional disease burden assessment system for children with neuroblastoma based on the Social Determinants of Health (SDH) theory, and to provide a reference for targeted assistance for rare diseases and for the optimization of health resource allocation.</p>Methods<p>An indicator pool was initially developed based on the SDH framework through a structured literature review and a structured expert panel discussion.

From November to December 2025, 20 of the 21 invited experts participated in two rounds of Delphi consultation to finalize the indicators, and the Analytic Hierarchy Process was employed to calculate indicator weights.</p>Results<p>The effective response rates of the 2 rounds of questionnaire surveys were 95.23% (20/21) and 100% (20/20), respectively. The expert authority coefficient was 0.885, and Kendall’s W coefficients were 0.123-0.452 and 0.118-0.236 for the 2 rounds (all P < 0.05), indicating high expert coordination.