Data · dataset · 2015
Human Risk Assessment for Nonylphenol
Listed in DataCite
ABSTRACTThis article presents a risk assessment for human exposure to nonylphenol (NP).
Description
We critically reviewed and assessed all relevant full-text publications based on a variety of data quality attributes. Two categories of data, environmental monitoring and biomonitoring from exposed individuals, were used to estimate human exposure to NP.
Environmental monitoring data included the measurement of NP in food, water, air, and dust. From these data and estimates of human intake rates for the sources, exposures were estimated from each source and source-specific Margins of Exposure (MOEs) calculated. However, the nature of the populations studied prevented the calculation of aggregate exposure calculations from these data.
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Rather, the most reliable estimates of aggregate exposure to NP were those derived from biomonitoring studies in exposed individuals. Using the daily absorbed dose estimates for NP, MOEs were calculated for these populations. The MOEs were based on the use of a No-Observed-Adverse-Effect-Level (NOAEL) for sensitive toxicological endpoints of interest, that is, systemic and reproductive toxicity from continuous-feeding more than 3.5 generations (13 mg/kg/day).
The MOEs were all greater than 1000 (ranging from 2863 to 8.4 × 10 7 ), clearly indicating reasonable certainty of no harm for source-specific and aggregate (based on biomonitoring) exposures to NP.
Links
Where it is published
- Repository landing page tandf.figshare.com/articles/dataset/Human_Risk_Assessment_for_Nonylphenol/1286921… ↗
landing page · from DataCite
- DOI doi.org/10.6084/m9.figshare.1286921.v2 ↗
DOI / persistent id · from DataCite
Documentation and papers
- Creative Commons Attribution 4.0 International creativecommons.org/licenses/by/4.0/legalcode ↗
license · from DataCite
- IsSupplementTo 10.1080/10807039.2014.999520 doi.org/10.1080/10807039.2014.999520 ↗
publication · from DataCite
Catalogue records · 2
- DataCite API api.datacite.org/dois/10.6084/m9.figshare.1286921.v2 ↗
metadata API · from DataCite
- DataCite Commons commons.datacite.org/doi.org/10.6084/m9.figshare.1286921.v2 ↗
catalogue entry · from DataCite
Topics
- Stated by source
- Biological sciences · Health sciences
- From keywords
- Chemistry · Ecology · Life Sciences · Research, science and technology policy
Related
- Has versionHuman Risk Assessment for Nonylphenol
- Possibly the same asHuman Risk Assessment for Nonylphenol
Provenance · 1 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| DataCite | 10.6084/m9.figshare.1286921.v2 | 13 d ago | JSON v1 |
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|---|---|---|---|
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| byte_size | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:biological-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:health-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Chemistry'] |
| concepts[field].local:field:life-sciences | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Biological Sciences'] |
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| description | source · DataCite | connector:datacite@1.0.0 | /data/attributes/descriptions |
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| updated_date | source · DataCite | connector:datacite@1.0.0 |