Alkaloids and phenolic constituents from Buteae Monospermae semen-raw data

Finally, 20 compounds were obtained, including 3R_ [(3, s_format_ β _ lactam), ethyl acetate] _ hydroxyindole (1), oleurol (2), 2 (3,4,5-dihydroxyphenyl) _1,3-dioxaldehyde-5-aldehyde (3), lanceolatin B (4), dihydroquercetin (5), and o Ⅴ alifolin(6) 、2_(2_methoxyphenyl)furo[2 ,3_h]chromen_ 4_one(7) 、pongapin(8) 、desmethoxy kanugin (9) 、2_(1 ,3_benzodioxol_5_yl)_3 ,6_dimethoxy_4H_1_benzopyran_4_one (10) 、 (2s)_3 ,4 , _methylenedioxy_6 Nie, 6 Nie, dimethylchromeno_ [2 Nie, 3 Nie: 7,8] _fla V anone (11), 6, 6, d_dimethylpyrano [2, 3,: 7,8] fla_ V one(12) 、3_hydroxyisolanchoearpin(13) 、_(4_hydroxyphenyl)_3_methoxy_4H_chromen_4_one (14) 、 Dye lignin (15), dye lignin 7_0_ β - d_furanosyl_ (1 → 6) _0_ β - d_glucopyranoside (16), _ (4_ hydroxy_3 methoxyphenyl) _ 5_ ethoxydecan_3 _one (17), anti hydroxycinnamic acid (18), ethyl paraben (19), uridine (20).

Among them, compounds 1 and 20 are alkaloids, compounds 2-15, 17-19 are phenolic acids, and compound 16 is a phenolic glycoside. Compounds 1~3 and 13~20 were isolated from purple rivet for the first time. The MTS method was used to evaluate the cell proliferation activity of compound 1 at concentrations greater than 25 0 μ mol/L can promote the proliferation of RAW 264.7 macrophages.