Table · dataset · 2026
Urinary neopterin and cortisol in greater spear-nosed bats
Listed in figshare and Loughborough Research Repository — shown once because both records carry DOI 10.6084/m9.figshare.32411784.v1
<p dir="ltr">This data file contains estimates of neopterin and cortisol measured by ELISA or gas chromatography/tandem mass spectrometry in urine of greater spear-nosed bats.
Description
Neopterin is used as a biomarker of inflammation because it is a byproduct of macrophage activation. Neopterin concentration typically increases with age in humans and other primates but has not been studied in bats.
Given that bats are particularly long-lived mammals for their size, studying neopterin across the lifespan may reveal whether individuals are resistant to age-related changes in immune activation. We used Enzyme Linked Immunosorbent Assay (ELISA) to estimate neopterin concentration in urine samples collected from wild greater spear-nosed bats (<i>Phyllostomus hastatus</i>) in Trinidad. Greater spear-nosed bats have an extremely polygynous mating system, with male mortality rates nearly double that of females.
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We estimated age from recaptures, an epigenetic clock, or tooth-wear. To biologically validate neopterin concentrations, we used ELISA and gas chromatography-tandem mass spectrometry to estimate urinary cortisol, a glucocorticoid that responds to inflammation. Consistent with expectations, neopterin levels were positively associated with cortisol levels in both sexes.
Unexpectedly, neopterin levels were negatively related to age in males, but independent of age in females. These results suggest that greater spear-nosed bats exhibit sex differences in age-related changes in immune activation that may relate to their female-biased survival.</p>
Links
Where it is published
- DOI doi.org/10.6084/m9.figshare.32411784.v1 ↗
DOI / persistent id · from figshare com
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare com
Topics
- From keywords
- Animal immunology · Animal immunology · Astronomy & Astrophysics · Behavioural ecology · Behavioural ecology · Chemistry · Chemistry · Computer Science & AI · Computer Science & AI · Earth & Environmental Science · Earth & Environmental Science · Ecological physiology · Ecological physiology · Economics & Finance · Economics & Finance · Engineering · Engineering · Humanities · Humanities · Life Sciences · Life Sciences · Materials Science · Mathematics & Statistics · Medicine & Health · Medicine & Health · Ocean & Atmospheric Science · Psychology & Behavioral Science · Psychology & Behavioral Science · Social Science · Social Science
- Inferred from text
- Mass spectrometry 75%
Provenance · 2 source records, 36 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| figshare | oai:figshare.com:article/32411784 | 4 d ago | JSON v1 |
| Loughborough Research Repository | oai:figshare.com:article/32411784 | 4 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].anzsrc:field:310301 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Behavioural ecology'] |
| concepts[field].anzsrc:field:310301 | mapping · repository lboro ac uk | vocabulary-mapper@1.0.0 | keywords['Behavioural ecology'] |
| concepts[field].anzsrc:field:310303 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Ecological physiology'] |
| concepts[field].anzsrc:field:310303 | mapping · repository lboro ac uk | vocabulary-mapper@1.0.0 | keywords['Ecological physiology'] |
| concepts[field].anzsrc:field:310905 | mapping · repository lboro ac uk | vocabulary-mapper@1.0.0 | keywords['Animal immunology'] |
| concepts[field].anzsrc:field:310905 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Animal immunology'] |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:materials-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:mathematics-statistics | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:social-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[modality].local:modality:mass-spectrometry | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/description |
| license | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare com | connector:figshare_com@1.0.0 | |
| title | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/title |