Dataset on the Mediating Role of Insulin Resistance Between Hypertension and NAFLD and Risk Prediction Models: Evidence from Large-Scale Machine Learning and Mediation Analysis

It was used to investigate the mediating role of insulin resistance (IR) in the relationship between hypertension and non-alcoholic fatty liver disease (NAFLD), and to evaluate the predictive value of multiple IR surrogate indices in NAFLD risk modeling.The dataset contains:Figure S1: Correlation matrix heatmaps of IR surrogate indices and NAFLD in hypertensive and non-hypertensive groups;Table S1: Pearson correlation coefficients and significance levels between variables and NAFLD in the hypertensive group;Table S2: Pearson correlation coefficients and significance levels between variables and NAFLD in the non-hypertensive group;Table S3: Baseline characteristics of individuals with and without NAFLD.This dataset provides evidence for exploring the “hypertension–IR–NAFLD” pathway and supports large-scale mediation analysis and machine learning modeling for NAFLD risk prediction.