Omics · study · 2026
Neurotranscriptomics of mutualistic cleaning in Ladridae wrasses
Listed in NCBI GEO
Despite the astonishing diversity of life, evolutionary biologists have documented numerous instances where species converge in how they behave, look, and function.
Description
Given the importance of happenstance in evolution, it is often assumed that mechanisms driving independent evolution of similar phenotypes (convergence) are distinct; yet recent discoveries suggest that conserved genomic mechanisms can underlie convergent traits.
Here, we generate forebrain transcriptomes from six sympatric Labridae wrasses that vary in mutualistic cleaning behavior and apply differential gene expression, co-expression, and phylogenetic comparative analyses to address three questions. First, do neurotranscriptomes vary among species with distinct cleaning behavior? Second, do species that have independently evolved facultative cleaning share neurotranscriptomic patterns?
Read the rest (2 more)
Third, are transcriptomic signatures linked to facultative cleaning also expressed in obligate cleaners? We identify shared neurotranscriptomic patterns in the repeated evolution of facultative cleaning, including 25 novel candidate genes. We then find that transcriptomic patterns associated with facultative cleaning are shared in our focal obligate cleaner species, with more genes than expected by chance with concordant expression patterns in obligate and facultative cleaners.
Our results illuminate the neuromolecular basis of cooperative behavior and demonstrate the predictive potential of comparative transcriptomics to unravel the mechanistic underpinnings of the repeated evolution of complex phenotypes.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE302nnn/GSE302322 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE302322 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1289865 ncbi.nlm.nih.gov/bioproject/PRJNA1289865 ↗
project · from NCBI GEO
- PubMed 42229923 pubmed.ncbi.nlm.nih.gov/42229923 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- Animal systematics and taxonomy 77%
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE302322 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:field:310401 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (77%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |