Omics · study · 2026
Sub-cellular System Drift Drives Mosaic Evolution of Mammalian Neurons
Listed in NCBI GEO
To examine the rate of evolutionary divergence between Mus musculus (C57BL/6) and Rattus norvegicus (Sprague–Dawley) dendritic transcriptome, we generated a rat sister datasets to a previously existing mouse dataset from our lab (GSE115480).
Description
We manually separated the dendrites and soma of pirimary rat hippocampal neurons using a micropipette and performed RNA-seq on each subcellular fraction as separate but paired subcellular transcriptomic experiments for each captured cell.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE341nnn/GSE341888 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE341888 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1504351 ncbi.nlm.nih.gov/bioproject/PRJNA1504351 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Rattus norvegicus
- From keywords
- Life Sciences
- Inferred from text
- Evolutionary biology 75% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE341888 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3104 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |