Data · collection · 2016
Effect of DOPA and dopamine coupling on protein loading of hydroxyapatite
Listed in DataCite
Hydroxyapatite (HA) is a promising carrier material for oral delivery of biomolecules such as proteins and drugs.
Description
Ways to increase the loading of such molecules on HA will lead to better nanomedicine. This study reports the surface functionalisation of HA particles using the mussel inspired molecules dopamine (DA) and 3,4-dihydroxy-L-phenylalanine (DOPA), in order to increase protein loading.
The adsorption mechanisms are discussed based on the adsorption isotherms, zeta potential, thermal analysis and theoretical models. Results show that DA functionalisation enhanced the loading, while DOPA functionalisation was ineffective.
Links
Where it is published
- Repository landing page figshare.com/collections/Effect_of_DOPA_and_dopamine_coupling_on_protein_lo… ↗
landing page · from DataCite
- DOI doi.org/10.6084/m9.figshare.c.2856088.v1 ↗
DOI / persistent id · from DataCite
Documentation and papers
- CC-BY creativecommons.org/licenses/by/3.0/us ↗
license · from DataCite
- IsSupplementTo 10.1179/1753555715y.0000000048 doi.org/10.1179/1753555715y.0000000048 ↗
publication · from DataCite
Catalogue records · 2
- DataCite API api.datacite.org/dois/10.6084/m9.figshare.c.2856088.v1 ↗
metadata API · from DataCite
- DataCite Commons commons.datacite.org/doi.org/10.6084/m9.figshare.c.2856088.v1 ↗
catalogue entry · from DataCite
Topics
- Stated by source
- Biological sciences · Clinical medicine · Physical sciences
- From keywords
- Biochemistry and cell biology · Immunology
Related
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| DataCite | 10.6084/m9.figshare.c.2856088.v1 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| concepts[field].fos:biological-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:clinical-medicine | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:physical-sciences | source · DataCite | connector:datacite@1.0.0 | |
| created_date | source · DataCite | connector:datacite@1.0.0 | |
| description | source · DataCite | connector:datacite@1.0.0 | /data/attributes/descriptions |
| license | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| publication_date | source · DataCite | connector:datacite@1.0.0 | /data/attributes/dates |
| title | source · DataCite | connector:datacite@1.0.0 | /data/attributes/titles/0/title |
| updated_date | source · DataCite | connector:datacite@1.0.0 |