Data · dataset · 2024
Spatial transcriptomics data of mouse thymus
Listed in ScienceDB
The thymus is a critical organ for T cell development and immune system function, but it undergoes significant structural and functional changes during aging, a process known as thymic involution.
Description
To investigate the spatial and cellular changes associated with thymic aging, we performed single-cell spatial transcriptomics on thymic tissues from young (4-week-old) and aged (52-week-old) C57BL/6J mice, with three biological replicates per age group.
This dataset provides a detailed spatial and cellular map of the thymus at single-cell resolution, capturing changes in cell types, abundances, and spatial organization during aging. The results offer valuable insights into the cellular and spatial heterogeneity of the thymus and provide a resource for understanding immune system aging and potential therapeutic strategies.
Links
Where it is published
- DOI doi.org/10.57760/sciencedb.18291 ↗
DOI / persistent id · from scidb cn
Catalogue records · 1
- OAI-PMH record scidb.cn/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=10.57760%2… ↗
metadata API · from scidb cn
Topics
- From keywords
- Earth & Environmental Science · Engineering · Humanities · Life Sciences · Social Science
- Inferred from text
- Zoology 68%
Provenance · 1 source records, 11 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ScienceDB | 10.57760/sciencedb.18291 | 9 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].anzsrc:group:3109 | enrichment · scidb cn | taxonomy-embedding@1.0.0 | title+keywords+description (68%) |
| concepts[field].local:field:earth-environmental | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:engineering | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:humanities | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:social-science | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| description | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/description |
| license | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/rights |
| publication_date | source · scidb cn | connector:scidb_cn@1.0.0 | |
| title | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/title |