Data · study · 2026
Expression data from budding yeast sec12-4 and sec12-4 ino2Δino4Δ mutant cells
Listed in NCBI GEO
Sec12 is a guanine nucleotide exchange factor (GEF) required for the initiation of COPII vesicle formation in ER to Golgi transport.
Description
The sec12-4 mutant cells show temperature sensitivity in growth and a defect in ER-to-Golgi protein transport. Ino2/Ino4 are components of the heteromeric basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs) and are required for derepression of phospholipid biosynthetic genes in response to inositol depletion.
We used microarrays to compare the global gene expression profiles between sec12-4 and sec12-4 ino2Δino4Δmutant cells.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE168nnn/GSE168638 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE168638 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA713304 ncbi.nlm.nih.gov/bioproject/PRJNA713304 ↗
project · from NCBI GEO
- PubMed 42399612 pubmed.ncbi.nlm.nih.gov/42399612 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Saccharomyces cerevisiae
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE168638 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:4932 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |