THE NEUROPHYSIOLOGICAL BASIS FOR EMOTIONAL MAINTENANCE AND REDUCED GOAL-DIRECTED BEHAVIOR IN SCHIZOPHRENIA

Event-related potentials (ERPs) were recorded from 27 SCZ outpatients and 23 healthy controls (CN) during an emotional maintenance task in which participants were presented an initial image for 3 seconds and then required to maintain a mental representation of the intensity that image over a delay period of varying lengths and determine whether the initial image was more or less intense than the second image.

The Late Positive Potential (LPP) was used as a neurophysiological marker of emotional maintenance during the delay period. SCZ showed normal in-the-moment emotion experience to positive stimuli; however, SCZ rated negative and neutral pictures as more intense than CN. SCZ also displayed deficits in emotional maintenance accuracy.