Data · dataset · 2026
A frozen host-anchored framework identifies a host-coupled Klebsiella pneumoniae-centered ecological signal in colorectal cancer
Listed in ScienceDB
This dataset provides reanalysis data and scripts for host–microbe coupling analysis in colorectal cancer (CRC), based on previously published, publicly available, de-identified human datasets.
Description
It contains host transcriptome expression matrices, paired microbial abundance tables, external stool microbiome benchmarking cohorts, and analysis scripts used for host anchoring, Kp-centered ecological score (KpNS) calculation, paired host–microbe coupling analysis, robustness analyses, and figure reproduction.
Data sources include TCGA_CRC, ERP155818, PRJEB27928, SRP114892, PRJNA404030, and PRJNA941834. The dataset is intended to support reproducibility of a frozen host-anchored framework in CRC and to facilitate recalculation of the 10-gene IMI, 5-bug KpNS, paired host-coupling, bootstrap, leave-one-out, permutation, and technical adjustment results. It includes processed expression matrices, microbial tables, and analysis scripts, and may be used for method reproduction, secondary analysis, and teaching.
Links
Where it is published
- DOI doi.org/10.57760/sciencedb.32127 ↗
DOI / persistent id · from scidb cn
Catalogue records · 1
- OAI-PMH record scidb.cn/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=10.57760%2… ↗
metadata API · from scidb cn
Topics
- From keywords
- Earth & Environmental Science · Engineering · Humanities · Life Sciences · Social Science
- Inferred from text
- Cancer 75% · Sequence analysis 76%
Provenance · 1 source records, 11 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ScienceDB | 10.57760/sciencedb.32127 | 8 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[disease].local:disease:cancer | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:field:310206 | enrichment · scidb cn | taxonomy-embedding@1.0.0 | title+keywords+description (76%) |
| concepts[field].local:field:earth-environmental | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:engineering | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:humanities | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:social-science | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| description | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/description |
| license_text | source · scidb cn | connector:scidb_cn@1.0.0 | |
| publication_date | source · scidb cn | connector:scidb_cn@1.0.0 | |
| title | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/title |