Omics · study · 2026
Characterization of Persistency of Lay in Laying Hens
Listed in NCBI GEO
Selective breeding in laying hens has resulted in a laying rate of approximately one egg per day during their first year.
Description
Due to variability within a flock, this rate declines after the first year, leading producers to cull hens. The aim of this study was to identify physiological and molecular differences between persistent (PL, egg-laying rate = 100%) and non-persistent layers (NPL, egg-laying rate ≤ 82%) after the first year.
Forty laying hens were reared from 16 to 76 weeks of age and a subset was maintained until 96 weeks. Throughout the study, egg-laying data were recorded daily. At 76 weeks, ovarian tissue was collected from PL (n=3) and NPL (n=4) hens for RNA-sequencing.
Read the rest (1 more)
Ovarian RNA-sequencing analysis revealed 279 differentially expressed genes between PL and NPL hens and analysis predicted the estrogen receptor as an upstream regulator. A greater understanding of the physiology and molecular patterns of persistent hens could enhance production efficiency and provide insights into ovarian aging in women.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE294nnn/GSE294546 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE294546 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1250476 ncbi.nlm.nih.gov/bioproject/PRJNA1250476 ↗
project · from NCBI GEO
- PubMed 41060289 pubmed.ncbi.nlm.nih.gov/41060289 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Gallus gallus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE294546 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9031 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |