Circulating concentrations of progestins used in contraception

The dataset consists of tables supplementary to the manuscript "Pharmacokinetics, metabolism and serum concentrations of progestins used in contraception", submitted to the journal Pharmacology & Therapeutics. In part of this manuscript we discuss possible reasons for the wide inter-individual and inter-study variability in reported serum progestin concentrations.

The data was sourced through extensive PubMed searches for serum or plasma concentrations of progestins used in various methods of administration e.g. intramuscular injection, subdermal implant or combined oral contraceptive. The columns in these tables include progestin concentrations (in nanomolar[nM]/picomolar [pM] or nanograms/milliliter [ng/ml] or picograms/milliliter [pg/ml]) for several different progestins, the concentrations of endogenous estrogen or progesterone or exogenous ethinyl estradiol, the model system used (number of women, any other drugs used in combination, other demographics), the method of quantification used (typically radioimmunoassay [RIA] or liquid chromatography with mass spectrometry [LC-MS]) and the citation for the original reference (listed at the end of each table).