Table · dataset · 2026
Table 1_Baseline BMI and weight change in dilated cardiomyopathy: associations with LVEF, BNP, and NYHA class.pdf
Listed in figshare and Loughborough Research Repository — shown once because both records carry DOI 10.3389/fcvm.2026.1901876.s001
Background and Aims<p>Baseline body mass index (BMI) and longitudinal weight change capture different clinical dimensions.
Description
We examined their concurrent associations with 12-month changes in left ventricular ejection fraction (LVEF), B-type natriuretic peptide (BNP), and New York Heart Association (NYHA) functional class among patients with dilated cardiomyopathy.</p>Methods<p>Of 600 records screened, 322 patients had complete paired baseline and 12-month measurements and were included in this retrospective cohort analysis.
Percentage weight loss was calculated as 100 × (baseline weight−12-month weight)/baseline weight; negative values denoted weight gain. Joint models included baseline BMI and weight loss and adjusted for age, sex, log-transformed baseline BNP, baseline LVEF, left ventricular end-diastolic diameter, baseline NYHA class, diabetes, chronic kidney disease, atrial fibrillation, and coronary atherosclerosis.</p>Results<p>Thirty-six patients gained weight, six demonstrated no weight change, and 280 lost weight.
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Baseline BMI was not independently associated with LVEF change (β = −0.099, 95% CI −0.269 to 0.071; P = 0.254), BNP log ratio (β = 0.008, 95% CI −0.014 to 0.030; P = 0.467), or NYHA improvement (OR = 1.02, 95% CI 0.94–1.10; P = 0.709). Each 5% greater weight loss was concurrently associated with a greater increase in LVEF (β = 2.43 percentage points, 95% CI 1.66–3.20), a lower BNP log ratio (β = −0.317, 95% CI −0.415 to −0.219), and higher odds of NYHA improvement (OR = 1.93, 95% CI 1.38–2.74; all P < 0.001).
The associations remained consistent after adjustment for the availability of heart-failure and weight-management therapies.</p>Conclusions<p>Twelve-month weight change was associated with concurrent changes in LVEF, BNP, and functional status, whereas baseline BMI was not. These data do not establish temporal direction, causality, or the superiority of weight change as a clinical marker.</p>
Links
Where it is published
- DOI doi.org/10.3389/fcvm.2026.1901876.s001 ↗
DOI / persistent id · from figshare com
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare com
Topics
- From keywords
- Astronomy & Astrophysics · Cardiology · Cardiology · Chemistry · Chemistry · Computer Science & AI · Computer Science & AI · Earth & Environmental Science · Earth & Environmental Science · Economics & Finance · Economics & Finance · Engineering · Engineering · Humanities · Humanities · Life Sciences · Life Sciences · Materials Science · Mathematics & Statistics · Medicine & Health · Medicine & Health · Ocean & Atmospheric Science · Psychology & Behavioral Science · Social Science · Social Science
- Inferred from text
- Cardiomyopathy 75% · Disease 75% · Heart 75% · Longitudinal study 65% · Tabular 65%
Provenance · 2 source records, 35 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| figshare | oai:figshare.com:article/33992860 | 11 d ago | JSON v1 |
| Loughborough Research Repository | oai:figshare.com:article/33992860 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare com | connector:figshare_com@1.0.0 | |
| concepts[anatomy].local:anatomy:heart | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[disease].local:disease:cardiomyopathy | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[disease].local:disease:disease | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:field:320101 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Cardiology'] |
| concepts[field].anzsrc:field:320101 | mapping · repository lboro ac uk | vocabulary-mapper@1.0.0 | keywords['Cardiology'] |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:materials-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:mathematics-statistics | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[method].local:method:longitudinal-study | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:tabular | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (65%) |
| description | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/description |
| license | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare com | connector:figshare_com@1.0.0 | |
| title | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/title |