Data from: Mutational effects depend on ploidy level: all else is not equal

This empirical result demonstrates that it cannot be assumed that mutations will have the same effect in haploids and homozygous diploids.

Usage notes

Tolerance parameter estimates from ML combined_A_AA_MLc.csv BMN parameters for graphing Parameters for data points (colours, position, pch etc.) from Gerstein et al. (Genetics, 2012) dataset. 1207NBMnys_param.csv Tolerance log-likelihood results from ML models Results from ML models for the three tolerance parameters (IC50, a50, m). NysIC50_A_AA_modelsig.csv R code to produce Figure1 (Tolerance data) 1209 Figure1.R R code to produce Figure2 (Bioscreen data) R code for Figure 2.

Includes statistical analysis for the bioscreen data. 1207 Figure2_GR.R Bioscreen data Growth rate data required to produce Figure 2. A_AA_rawdata.csv