Data · dataset · 2026
Development of antibody technologies to produce novel therapeutic and diagnostic applications
Listed in ZivaHub and Deakin Research Online and DMU Figshare — shown once because both records carry DOI 10.17034/32638758.v1
Problems with steroid analysis in a clinical lab have been well characterized over the years, and organizations have issued position statements and recommendations on androgen-disorder diagnostics.
Description
This research aims to discover and develop an antibody highly specific for testosterone with minimal cross-reactivity to DHEA and other steroids using a combination of classical hybridoma technologies and in silico engineering techniques.
By assessing the docking energies of testosterone and other steroids to the selected antibody molecular dynamics was employed to observe potential conformational changes in the binding process. This information will aid in further developing the antibody for affinity maturation and specificity optimization.<br><br><i>Thesis is embargoed until 31 December 2028</i>.<br><br><br>
Links
Where it is published
- DOI doi.org/10.17034/32638758.v1 ↗
DOI / persistent id · from zivahub uct ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from zivahub uct ac za
Topics
- From keywords
- Applied immunology · Applied immunology · Applied immunology · Bioinformatics and computational biology · Bioinformatics and computational biology · Bioinformatics and computational biology · Clinical chemistry · Clinical chemistry · Clinical chemistry · Earth & Environmental Science · Earth & Environmental Science · Earth & Environmental Science · Engineering · Engineering · Engineering · Life Sciences · Life Sciences · Life Sciences
Provenance · 3 source records, 23 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ZivaHub | oai:figshare.com:article/32638758 | 12 d ago | JSON v1 |
| Deakin Research Online | oai:figshare.com:article/32638758 | 12 d ago | JSON v1 |
| DMU Figshare | oai:figshare.com:article/32638758 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].anzsrc:field:320202 | mapping · zivahub uct ac za | vocabulary-mapper@1.0.0 | keywords['diagnostics'] |
| concepts[field].anzsrc:field:320202 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['diagnostics'] |
| concepts[field].anzsrc:field:320202 | mapping · dro deakin edu au | vocabulary-mapper@1.0.0 | keywords['diagnostics'] |
| concepts[field].anzsrc:field:320402 | mapping · zivahub uct ac za | vocabulary-mapper@1.0.0 | keywords['antibody engineering'] |
| concepts[field].anzsrc:field:320402 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['antibody engineering'] |
| concepts[field].anzsrc:field:320402 | mapping · dro deakin edu au | vocabulary-mapper@1.0.0 | keywords['antibody engineering'] |
| concepts[field].anzsrc:group:3102 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['computational biology'] |
| concepts[field].anzsrc:group:3102 | mapping · zivahub uct ac za | vocabulary-mapper@1.0.0 | keywords['computational biology'] |
| concepts[field].anzsrc:group:3102 | mapping · dro deakin edu au | vocabulary-mapper@1.0.0 | keywords['computational biology'] |
| concepts[field].local:field:earth-environmental | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:engineering | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| description | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/description |
| license_text | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| publication_date | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| title | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/title |