Text · study · 2026
Transcriptomic profiling of CCL2-high and CCL2-low glioma cell states
Listed in NCBI GEO
Glioma cells can reversibly occupy cellular states with distinct contributions to tumor growth and microenvironmental remodelling.
Description
To define transcriptional programmes associated with endogenous Ccl2 activity, CCL2-high and CCL2-low cells were isolated from endogenous Ccl2 reporter cells by fluorescence-activated cell sorting and analysed using one-colour gene-expression microarrays. The resulting profiles were used to identify genes and pathways preferentially represented in the CCL2-high niche-remodelling state or the CCL2-low proliferative state.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE345nnn/GSE345749 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE345749 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1521802 ncbi.nlm.nih.gov/bioproject/PRJNA1521802 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Rattus norvegicus
- From keywords
- Life Sciences
- Inferred from text
- Cancer 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE345749 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |