<p>NHR-68 inhibits immune pathways.</p>

Data are presented from three independent experiments, with 90 animals per condition per experiment (<i>N</i> = 3; <i>n</i> = 90 animals per condition per experiment). The Kaplan–Meier method was used to calculate the survival fractions, and statistical significance between survival curves was determined using the log-rank test. <b><i>(E)</i></b> Survival of wild-type and <i>nhr-68(gk708)</i> animals fed empty vector control or <i>daf-16</i> RNAi followed by exposure to <i>P. aeruginosa</i>.

Mean survival times were 2.40 and 3.01 days for empty vector control RNAi and 2.14 and 2.43 days for <i>daf-16</i> RNAi, respectively. Wild-type vs. <i>nhr-68(gk708)</i>, <i>p</i> < 0.0001 and <i>p</i> = 0.0130 for empty vector control and <i>daf-16</i> RNAi, respectively. Data are presented from three independent experiments, with 90 animals per condition per experiment (<i>N</i> = 3; <i>n</i> = 90 animals per condition per experiment).

The Kaplan–Meier method was used to calculate the survival fractions, and statistical significance between survival curves was determined using the log-rank test. The data underlying this Figure can be found in <a href="plosbiology.org/article/info:doi/10.1371/journal.pbio.3004026#pbio.3004026.s009" target="_blank">S1 Data</a>.</p>