Data · dataset · 2025
T Regulatory Cells: A Double-Edged Sword in HCC Diagnosis and Prognosis
Listed in Teesside University Research Data Repository
Hepatocellular carcinoma (HCC) stands among the deadliest cancers worldwide, and part of its resilience lies in its ability to manipulate the immune system.
Description
Within the tumour microenvironment (TME), regulatory T cells (Tregs) characterized by the markers CD4+CD25+FoxP3+ play a paradoxical role. While they are vital for maintaining immune balance under normal conditions, in the context of HCC, they suppress anti-tumour responses, helping the cancer evade immune detection.
Tregs show significant potential as both diagnostic and prognostic markers. However, targeting them for therapy remains a complex endeavour. In this piece, I explore how a deeper understanding of Tregs could reshape the clinical management of HCC, while acknowledging the challenges posed by their dual roles
Links
Where it is published
- DOI doi.org/10.17632/r37hykxvrs.1 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Earth & Environmental Science · Life Sciences · Medicine & Health
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/r37hykxvrs.1 | 8 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |