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Table · dataset · 2026

PAGODA dataset

Listed in figshare

<p dir="ltr">This dataset contains computational design outputs and experimental screening results associated with PAGODA, a method for designing partially overlapping protein-coding sequences.

Description

The files link sequence designs and Potts model scores to enrichment measurements and plate-based growth assessments.</p><p dir="ltr">The dataset includes five CSV files:</p><ul><li><b>hisI_purE_enrichment.csv</b> — 200 records for hisI–purE designs, including nucleotide sequences, frame and overlap annotations, gene-specific enrichment measurements, recomputed Potts scores, and insertion, deletion, and substitution counts.</li><li><b>purE_hisI_enrichment.csv</b> — 200 records for the reverse gene order, purE–hisI, with the same design annotations and enrichment measurements.</li><li><b>ilvE_gltA_enrichment.csv</b> — 445 records for ilvE/gltA designs in both gene orders.

Includes sequence and library-design information, primers, Potts scores, condition-specific counts and enrichment values across three replicates, and summary enrichment statistics.</li><li><b>purE_hisI_plate.csv</b> — Growth assessments for 24 purE–hisI designs under no supplementation, histidine supplementation, and adenine supplementation at 24 and 96 hours, together with functional classifications.</li><li><b>screen_results.sample.csv</b> — A sample of 99 computational screening records across multiple gene pairs, including designed nucleotide sequences, initial and optimized protein sequences, sequence coordinates, overlap lengths, scores, insertion/deletion annotations, and design parameters.</li><li><b>screen_results.csv</b> — The full result in the same format as the <b>screen_results.sample.csv</b> </li></ul><p dir="ltr">Files are provided in comma-separated format and can be opened using spreadsheet software or standard data-analysis tools.

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Blank entries indicate values not provided in the files and should not be interpreted as zero. Associated code is available at <a href="github.com/BiosecSFA/PAGODA" target="_blank">github.com/BiosecSFA/PAGODA</a>.</p>

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Provenance · 1 source records, 18 field assertions
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figshareoai:figshare.com:article/337526714 d agoJSON v1
FieldAssertionExtractorEvidence
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concepts[field].anzsrc:field:310606mapping · figshare comvocabulary-mapper@1.0.0keywords['Industrial molecular engineering of nucleic acids and proteins']
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