Excel · study · 2026
Deficiency in plastid EF-Tu elicits DNA damage response in Arabidopsis thaliana
Listed in NCBI GEO
Arabidopsis RAB8D (AT4G20360) encodes the plastid translation factor EF-Tu, which is crucial for plant viability.
Description
We wondered about the connection between RAB8D deficiency and DNA damage response. RNA-seq results revealed significant upregulation of DNA repair-related genes in rab8d-2, a knock-down mutant of RAB8D.
Introducing the knockout allele of ATM (atm-2), SOG1 (sog1-1), NAC044 (nac044-1), or NAC085 (nac085-1) into rab8d-2 significantly reduced the expression of DNA repair-related genes.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316944 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316944 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1405573 ncbi.nlm.nih.gov/bioproject/PRJNA1405573 ↗
project · from NCBI GEO
Topics
- Stated by source
- Arabidopsis thaliana · Expression profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE316944 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:3702 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |