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Data · dataset · 2025

Data from: Coevolution of cooperative lifestyles and reduced cancer prevalence in mammals

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Why cancer is so prevalent among mammals, despite the fact that some species evolved resistance mechanisms, remains an open question.

Description

We hypothesized that cancer prevalence and mortality risk might have been fine-tuned by evolution. Using public databases, we show that species with cooperative habits have lower cancer prevalence and mortality risk.

By developing a mathematical model, we provide a mechanistic explanation: an oncogenic variant that elicits higher cancer mortality in older and less reproductive individuals is detrimental to cooperative mammalian societies but can lead to a counterintuitive overcompensation in population size and fitness within competitive contexts. The phenomenon of a population increasing in response to a decrease in its per capita survival rate is called the hydra effect, a process never explored in the field of cancer before.

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Therefore, cancer can be considered as a selected mechanism of biological obsolescence in competitive species.

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Inferred from text
Cancer 75%
Provenance · 1 source records, 13 field assertions
SourceKeyLast seenRaw
DataCite10.5061/dryad.xgxd254vh10 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · DataCiteconnector:datacite@1.0.0/data/attributes/rightsList
byte_sizesource · DataCiteconnector:datacite@1.0.0
concepts[disease].local:disease:cancerenrichment · DataCitekeyword-concept-rules@1.0.0title+description (75%)
concepts[field].fos:basic-medicinesource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:biological-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:mathematicssource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:natural-sciencessource · DataCiteconnector:datacite@1.0.0
created_datesource · DataCiteconnector:datacite@1.0.0
descriptionsource · DataCiteconnector:datacite@1.0.0/data/attributes/descriptions
licensesource · DataCiteconnector:datacite@1.0.0/data/attributes/rightsList
publication_datesource · DataCiteconnector:datacite@1.0.0/data/attributes/dates
titlesource · DataCiteconnector:datacite@1.0.0/data/attributes/titles/0/title
version_labelsource · DataCiteconnector:datacite@1.0.0