Data Sheet 1_Case Report: In situ split liver transplantation from controlled donation after circulatory death donors assisted by normothermic regional perfusion: a case series.pdf

During NRP, lactate levels decreased substantially in both donors (from 6.6 to 1.2 mmol/L and from 9.5 to 4.1 mmol/L, respectively), with concurrent pH normalization. All recipients had functioning grafts at last follow-up (17.2–20.9 months). One infant developed early allograft dysfunction in association with hepatic artery thrombosis and underwent successful revascularization.

No recipient developed primary nonfunction, graft loss, or a clinically diagnosed biliary complication.</p>Conclusion<p>This case series supports the technical feasibility of NRP-assisted in situ SLT from cDCD donors and documents encouraging intermediate-term graft function. The small sample does not establish safety or comparative effectiveness. Larger studies with standardized viability assessment and extended vascular and biliary follow-up are required.</p>