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Table · dataset · 2026

Younger Age-Related Incidence of Corneal Limbitis Following Pterygium Excision Combined with Conjunctival-Limbal Autograft

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Description

<p>To investigate the incidence, clinical characteristics, and risk factors of corneal limbitis following pterygium excision with conjunctival-limbal autograft.</p> <p>This retrospective study included 63 eyes of 61 patients with primary nasal pterygium who underwent pterygium excision with conjunctival-limbal autograft. Patients were assessed perioperatively using anterior segment swept-source optical coherence tomography (AS SS-OCT; Anterion, Heidelberg, Germany), and postoperative complications were evaluated during follow-up.

Risk factors for corneal limbitis, including age and preoperative AS SS-OCT-guided morphological and optical parameters, were analyzed.</p> <p>Corneal limbitis occurred in 12 of 63 eyes (19.0%), with a mean onset of 19.1 ± 10.9 weeks postoperatively. Eyes with limbitis were significantly younger than those without (45.3 ± 8.1 vs. 60.5 ± 9.5 years, <i>p</i> < 0.001), while other demographic, clinical severity, and morphological parameters were not significantly different between the two groups.

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On multivariate logistic regression analysis, younger age was the only independent risk factor for postoperative corneal limbitis (<i>p</i> = 0.007, OR = 0.674). ROC curve analysis identified a cutoff age of 49.5 years (AUC = 0.895, sensitivity 92.2%, specificity 83.3%). The incidence of corneal limbitis was significantly higher in patients younger than 50 years (10/14 eyes, 71.4%) than in those aged 50 years or older (2/49 eyes, 4.1%) (<i>p</i> < 0.001).

All limbitis cases resolved with anti-inflammatory treatment.</p> <p>Corneal limbitis may represent a notable postoperative complication following pterygium excision with conjunctival-limbal autograft, occurring predominantly in younger patients. Younger age appeared to be associated with a higher risk, although this finding requires validation in larger cohorts.</p>

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