Curated Chemicals Reported in Urine Biomonitoring Studies Using Non-Targeted Analyses (NTA)

Although these methods provide high-quality qualitative and quantitative data, they are inherently limited to relatively small sets of predefined chemicals and known metabolites. In contrast, non-targeted analysis (NTA) and suspect screening approaches enable substantially broader chemical characterization, providing opportunities to elucidate complex human exposure profiles.

Our objectives with this work were to collect data on chemicals reported in human urine biomonitoring media using NTA methods and to harmonize this information into a database. We conducted a literature search and identified 50 relevant publications. For each publication, we manually extracted structural information for chemicals detected in consumer products or their extracts, along with metadata including chromatographic methods and type of consumer product sampled.