Data · dataset · 2026
<p>Increased C1q deposition in glomeruli of MRL/lpr mice treated with curli.</p>
Listed in UCL Research Data Repository
<p>MRL/lpr mice were intraperitoneally injected weekly with <b>(A)</b> PBS or (<b>B</b>) curli purified from <i>Salmonella</i> Typhimurium for 6 weeks and euthanized at 13 weeks old.
Description
Frozen tissue sections were stained with goat anti-mouse IgG-AlexaFluor405 (blue), rat anti-mouse C3-AlexaFluor647 (red), and rat anti-mouse C1q-FITC (green). <b>(A-B)</b> Representative images of glomeruli by confocal microscopy (63X objective).
Sections shown are from two individual mice per group, scale bars represent 20 µm. <b>(C-F)</b> Images were quantified in ImageJ for mean fluorescence intensity (MFI) inside glomeruli of <b>(C)</b> IgG, <b>(D)</b> C3, <b>(E)</b> C1q, and (<b>F</b>) area was measured, within at least 15 glomeruli per mouse and averaged. Statistics: <b>(C-F)</b> Unpaired t-test (**p < 0.01).</p>
Links
Where it is published
- DOI doi.org/10.1371/journal.ppat.1014666.g006 ↗
DOI / persistent id · from rdr ucl ac uk
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from rdr ucl ac uk
Topics
- From keywords
- Biochemistry and cell biology · Earth & Environmental Science · Ecology · Immunology · Infectious diseases · Life Sciences · Medicine & Health · Microbiology · Virology
- Inferred from text
- Image 65% · Microscopy 75%
Provenance · 1 source records, 16 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| UCL Research Data Repository | oai:figshare.com:article/34049279 | 9 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].anzsrc:field:310706 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Virology'] |
| concepts[field].anzsrc:field:320211 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Infectious Diseases'] |
| concepts[field].anzsrc:group:3101 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Cell Biology'] |
| concepts[field].anzsrc:group:3103 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Ecology'] |
| concepts[field].anzsrc:group:3107 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Microbiology'] |
| concepts[field].anzsrc:group:3204 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Immunology'] |
| concepts[field].local:field:earth-environmental | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[modality].local:modality:image | enrichment · rdr ucl ac uk | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:microscopy | enrichment · rdr ucl ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| title | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | /metadata/dc/title |