Marmoset-human parcellation mapping

An integrated knowledge- and data-driven cross-species mapping algorithm was developed, implementing systematic brain network parcellation mapping through expert-defined biological correspondence across 15 functional networks.

Key findings from the mapping include: (1) Strong cross-species conservation of primary sensorimotor (visual, somatosensory, auditory) networks, though these networks occupy proportionally larger cortical areas in marmosets; (2) Significant evolutionary divergence in higher-order associative networks, with human default and control networks differentiating from single components into multiple subnetworks accompanied by substantial cortical expansion; (3) Complex evolutionary pathways in intermediate hierarchical networks (e.g., marmoset higher visual networks), which segregate into human dorsal attention and language networks; (4) Functional integration in the human action network, incorporating auditory and attentional components to form the salience/parietomemory network.