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Data · collection · 2015

Synthesis of [1,2,3]Triazolo[5,1- a ]isoquinoline Derivatives via a Selective Cascade Cyclization Sequence of 1,2-bis(Phenylethynyl)benzene Derivatives

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A direct, concise, synthetic method for the generation of [1,2,3]triazolo[5,1- a ]isoquinoline derivatives, using a selective cascade cyclization of unsymmetrical substituted 1,2-bis(phenylethynyl)benzene derivatives with NaN 3 , has been developed.

Description

The reaction gave different substituted [1,2,3]triazolo[5,1- a ]isoquinolines in moderate to good yields. It was found that the substituents on the alkynes were important for the selectivities of the cascade cyclization sequences.

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SourceKeyLast seenRaw
DataCite10.6084/m9.figshare.c.203865212 d agoJSON v1
DataCite10.6084/m9.figshare.c.2038652.v112 d agoJSON v1
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