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Omics · study · 2026

Identification of Enhancers and Transcription Factors Regulating Developmental and Functional Maturation of Skeletal Muscle [RNA-Seq]

Listed in NCBI GEO

We investigated transcriptional differences in skeletal muscle between neonatal and adult cattle using RNA sequencing (RNA-seq).

Description

A total of 2,785 differentially expressed genes (DEGs) were identified, including 1,416 upregulated and 1,369 downregulated genes in adult muscle compared with neonatal muscle. Genes upregulated in adult muscle included MYH7 and MB, whereas genes such as MYH3 and MYH8 were downregulated.

Notably, several canonical adult muscle markers, including MYH1 and MYH2, did not show significant differential expression between developmental stages.

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From keywords
Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32909211 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title