An overview of Phytophthora pathogenesis and to summarise progress in arginine-any amino acid-leucine arginine (RxLR) effector

We further reveal that the activity of PpRxLR4 is likely to be mediated by crucial IDR-associated AIMs encoded in this effector. In silico mutation analysis of SLiMs predicted damaging implications on structure stability and biological functions.

There is still a need for experimental validation of these mutations in planta to further support the effector’s role in mediating protein-protein interactions and effector function. In silico prediction and Y2H screening of potential interactors for PpRxLR4 revealed autophagy-related proteins and growth and development proteins could likely be the partners for this effector.</p>