Data · dataset · 2025
Probiotics improve acute gastrointestinal dysfunction in patients undergoing cardiopulmonary bypass surgery
Listed in Teesside University Research Data Repository
Acute gastrointestinal injury (AGI) after cardiopulmonary bypass (CPB) is one of the signs for poor prognosis.
Description
This study aimed to investigate the effect of preoperative probiotics supplementation on AGI. In this double-blind randomized controlled trial, patients undergoing heart valve replacement (HVR) with CPB were randomly assigned to receive either a probiotic (Lac group) or placebo (Placebo group).
The probiotic was given daily, for seven days before surgery. We demonstrated that preoperative supplementation of probiotics can improve the recovery of patients after CPB surgery by preventing acute gastrointestinal injury. Cardiac Surgery Score, and the duration of CPB ≥ 132 min are independent risk factors for the occurrence of AGI.
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In contrast, probiotics is a preventive factor for the occurrence of AGI. There was gut microbiota imbalance in patients who underwent HVR with CPB. The 16s rRNA showed that there was a difference in gut microbiota between two groups.
Links
Where it is published
- DOI doi.org/10.17632/j3hfvn28yy.2 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Earth & Environmental Science · Life Sciences · Medicine & Health
- Inferred from text
- Heart 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/j3hfvn28yy.2 | 21 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[anatomy].local:anatomy:heart | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |