A systematic review and meta-analysis of randomized controlled trials to investigate the impact of active body-weight-supported treadmill training on gait function of children and adolescents with cerebral palsy

No changes were observed in mobility, speed, stride length, cadence, and endurance. The certainty of the evidence for speed, endurance, TUG, stride length, and cadence was very low, and for GMFM was low.</p> <p>Active BWSTT may produce clinically relevant improvements in GMFM of children and adolescents with CP, whereas its effects on broader walking performance and underlying neural mechanisms remain uncertain. However, the low to very low certainty of evidence warrants further high-quality RCTs examining gait outcomes, brain plasticity, and their relationship.</p> <p></p><p>The aim of this study was to determine the efficacy of active body-weight supported treadmill training for children with cerebral palsy.</p><p>There is evidence showing significant improvements in standing and walking.</p><p>The training was safe without any reported adverse effects.</p><p>Clinicians should remain cautious in implementing this training due to the very low certainty of the evidence.</p><p></p> <p>The aim of this study was to determine the efficacy of active body-weight supported treadmill training for children with cerebral palsy.</p> <p>There is evidence showing significant improvements in standing and walking.</p> <p>The training was safe without any reported adverse effects.</p> <p>Clinicians should remain cautious in implementing this training due to the very low certainty of the evidence.</p>