Data · dataset · 2018
Supplementary data to publication “An approximate Bayesian significance test for genomic evaluations” (Biom J)
Listed in RADAR and RADAR4Memory — shown once because both records carry DOI 10.22000/80
A simulation study has been conducted to analyse the association between genetic and phenotypic variation in livestock.
Description
Following the density and distribution of single nucleotide polymorphisms (SNPs) on the Illumina BovineSNP50 chip, 52,773 SNPs were simulated on the cattle genome of 30 Morgan length. Several generations of random mating were executed in which random recombination events according to the genetic distance between SNPs and random mutation of SNP alleles were considered.
In the most recent generations, 50 sires were mated to 20 dams in order to generate multiple half-sib families. The data were split into training (n=2,000) and validation/testing set (n=2,000). Twenty-three SNPs were randomly preselected to be the causative variants, and additive, dominance and epistatic effects were simulated.
Read the rest (2 more)
Two different traits were achieved by adding different residual error terms to the sum of genetic effects, such that the total genetic variation contributed either 30% or 50% to the phenotypic variation. Then, 5,227 SNPs (every 10-th SNP including the causative variants) were selected. The simulation was repeated 100 times.
More details can be found in Wittenburg et al. (2011) Including non-additive genetic effects in Bayesian methods for the prediction of genetic values based on genome-wide markers. BMC Genetics 12:74, doi.org/10.1186/1471-2156-12-74
Links
Where it is published
- DOI doi.org/10.22000/80 ↗
DOI / persistent id · from radar service eu de
Catalogue records · 1
- OAI-PMH record radar-service.eu/oai/OAIHandler?verb=GetRecord&metadataPrefix=oai_dc&identifier… ↗
metadata API · from radar service eu de
Topics
- From keywords
- Earth & Environmental Science · Earth & Environmental Science · Genetics · Genetics · Life Sciences · Life Sciences
- Inferred from text
- Simulation 75%
Provenance · 2 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| RADAR | 10.22000/80 | 10 d ago | JSON v1 |
| RADAR4Memory | 10.22000/80 | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · radar service eu de | connector:radar_service_eu_de@1.0.0 | |
| concepts[field].anzsrc:group:3105 | mapping · radar service eu de | vocabulary-mapper@1.0.0 | keywords['Genetics'] |
| concepts[field].anzsrc:group:3105 | mapping · radar4memory radar service eu | vocabulary-mapper@1.0.0 | keywords['Genetics'] |
| concepts[field].local:field:earth-environmental | mapping · radar4memory radar service eu | connector:radar4memory_radar_service_eu@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · radar service eu de | connector:radar_service_eu_de@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · radar service eu de | connector:radar_service_eu_de@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · radar4memory radar service eu | connector:radar4memory_radar_service_eu@1.0.0 | |
| concepts[method].local:method:simulation | enrichment · radar service eu de | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · radar service eu de | connector:radar_service_eu_de@1.0.0 | /metadata/dc/description |
| license | source · radar service eu de | connector:radar_service_eu_de@1.0.0 | /metadata/dc/rights |
| publication_date | source · radar service eu de | connector:radar_service_eu_de@1.0.0 | |
| title | source · radar service eu de | connector:radar_service_eu_de@1.0.0 | /metadata/dc/title |