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Data · dataset · 2020

Data for: In silico prediction of bioequivalence of Isosorbide Mononitrate tablets with different dissolution profiles using PBPK modeling and simulation

Listed in Teesside University Research Data Repository

The research data files are compromise of 5 supplementary materials.

Description

The detailed information of clinical study is displayed in Supplementary material 1, and all simulated data in manuscript are shown in supplementary material 2-5: 1) supplementary material 1 (the detailed information of clinical study) 2) supplementary material 2 (the simulated data used for internal verification of PBPK model) 3) supplementary material 3 (the simulated data used for external verification of PBPK model) 4) supplementary material 4 (the simulated data used in the section 4.3 of manuscript) : this simulated data was used to explore whether the rapid dissolution rate (dissolved ≥ 85% in 30 min) are necessary to ensure the bioequivalence for BCS I class drug 5) supplementary material 5 (the simulated data used in the section 4.4 of manuscript) : this simulated data was used to establish a clinically relevant dissolution specification of Isosorbide Mononitrate tablets.

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Simulation 75%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
Teesside University Research Data Repositoryoai:data.mendeley.com/s5nb3bxyjf.17 h agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:earth-environmentalmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:medicine-healthmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[method].local:method:simulationenrichment · researchdata tees ac ukkeyword-concept-rules@1.0.0title+description (75%)
descriptionsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/description
licensesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/rights
publication_datesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
titlesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/title